Last update
5/14/2025

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 31 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 2 Softgels
Serving Per Container: 125
Amount Per Serving
%DV
Calories
20
 
Total Fat
2 g
3%**
Polyunsaturated Fat
0.5 g
 
Cholesterol
20 mg
7%
Total Carbohydrate
less than 1 g
<1%**
Protein
less than 1 g
 
Fish Oil
2000 mg
*
Total Omega-3 Fatty Acids
600 mg
*
Omega-3 EPA and DHA
500 mg
*
Omega-3 Other
100 mg
*

Top Medical Research Studies

9
Omega-3 EPA+DHA improves cholesterol
We conducted a comprehensive trial to understand how different types of omega-3 fatty acids affect cholesterol levels and inflammation in adults struggling with high cholesterol.

Over 12 weeks, participants took various doses of omega-3s, including EPA and DHA, revealing notable benefits. Those receiving higher doses of EPA and DHA saw their triglycerides drop significantly—by up to 15.78%—compared to controls.

Interestingly, ALA supplementation did not lead to improvements in cholesterol or inflammation status, highlighting the superior role of EPA and DHA in managing these health issues.
Read More
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.

Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
We examined how swapping a saturated fat diet for omega-3 polyunsaturated fatty acids (n-3PUFAs) affects cholesterol and bone health in hypercholesterolemic rats.

In our study, rats that shifted to an n-3PUFA diet saw a notable decrease in serum lipids. While the diet appeared to positively impact their bone loss linked to periodontitis, rats on the n-3PUFA diet showed results similar to those on a commercial diet, indicating no major advantage of fish oil over a balanced diet.

Overall, our findings suggest that while omega-3s can help with cholesterol, they don't offer significant improvements over typical diets in these conditions.
Read More

Most Useful Reviews

9
Good cholesterol increase
2 people found this helpful
I highly recommend this! It is an excellent product, functioning perfectly. I take it continuously throughout the year, and during my analysis, the doctor inquired: "Do you consume a lot of fish?" (I actually dislike fish and hardly eat it). Ultimately, the “good” cholesterol prevails over the “bad,” effectively removing it from my body, thanks to Omega.
Read More
7.5
Improved concentration
This helps me focus better on my work and has effectively lowered my cholesterol.
Read More
7.5
Cholesterol-lowering effects
This product boasts good quality with pure fish oil and beneficial ingredients. Suitable for all ages, it aids in maintaining health without any fishy taste. Omega is known for its heart support and appears to have anti-inflammatory and cholesterol-lowering effects.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 31 Researches
7.9
  • All Researches
9
Antarctic krill oil aids cholesterol
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.

While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
Read More
9
CA-rich fish oils lower cholesterol
We investigated whether cetoleic acid (CA), a healthy fat found in certain fish, can help lower cholesterol levels in rodents. Our systematic review included 12 studies, assessing how CA-rich fish oils influenced total cholesterol compared to regular diets.

The results showed a significant reduction in cholesterol levels in rodents that consumed CA-rich oils. However, it’s important to note that the risk of bias in the studies varied, making our conclusions tentative. Overall, these findings suggest CA-rich fish oils could play a beneficial role in heart health, but further research in humans is needed.
Read More
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.

Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
Read More
9
Omega-3 effective for heart risk
We examined the role of eicosapentaenoic acid (EPA), specifically icosapent ethyl, in reducing cardiovascular disease risks. Approved by the FDA, this omega-3 treatment showed a notable 25% reduction in major heart events for high-risk patients. These patients already had controlled cholesterol but elevated triglyceride levels.

Importantly, while EPA proved effective, mixed omega-3 products lacking substantial evidence for heart health did not provide the same benefits. We believe adding EPA-only formulations to cardiovascular prevention guidelines is essential for at-risk individuals.
Read More
9
8-HEPE benefits cholesterol management
We explored how 8-hydroxyeicosapentaenoic acid (8-HEPE), derived from Pacific krill, could improve cholesterol levels in mice commonly used for dyslipidemia studies.

Over eighteen weeks, mice on a high-cholesterol diet receiving 8-HEPE showed significantly higher levels of good HDL cholesterol, alongside lower levels of bad LDL cholesterol and liver triglycerides.

This suggests that 8-HEPE may enhance lipid profiles and liver health by influencing certain genes in macrophages. While promising, further research is needed to confirm these benefits in humans.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Good cholesterol increase
2 people found this helpful
I highly recommend this! It is an excellent product, functioning perfectly. I take it continuously throughout the year, and during my analysis, the doctor inquired: "Do you consume a lot of fish?" (I actually dislike fish and hardly eat it). Ultimately, the “good” cholesterol prevails over the “bad,” effectively removing it from my body, thanks to Omega.
Read More
7.5
Improved concentration
This helps me focus better on my work and has effectively lowered my cholesterol.
Read More
7.5
Cholesterol-lowering effects
This product boasts good quality with pure fish oil and beneficial ingredients. Suitable for all ages, it aids in maintaining health without any fishy taste. Omega is known for its heart support and appears to have anti-inflammatory and cholesterol-lowering effects.
Read More

Frequently Asked Questions

9
Good cholesterol increase
2 people found this helpful
I highly recommend this! It is an excellent product, functioning perfectly. I take it continuously throughout the year, and during my analysis, the doctor inquired: "Do you consume a lot of fish?" (I actually dislike fish and hardly eat it). Ultimately, the “good” cholesterol prevails over the “bad,” effectively removing it from my body, thanks to Omega.
7.5
Improved concentration
This helps me focus better on my work and has effectively lowered my cholesterol.
7.5
Cholesterol-lowering effects
This product boasts good quality with pure fish oil and beneficial ingredients. Suitable for all ages, it aids in maintaining health without any fishy taste. Omega is known for its heart support and appears to have anti-inflammatory and cholesterol-lowering effects.
8
Icosapent ethyl reduces cardiovascular events
We examined the effects of icosapent ethyl, a form of eicosapentaenoic acid, on patients with high cholesterol, specifically those who also have elevated triglyceride levels. In this analysis of the REDUCE-IT trial, we focused on statin-treated individuals who had a high risk of cardiovascular problems and found that the treatment could lower the occurrence of serious cardiovascular events.

The study included a significant number of patients who were divided based on their low-density lipoprotein cholesterol (LDL-C) levels. An interesting finding was that icosapent ethyl appeared to benefit both groups—those with LDL-C levels below 55 mg/dL and those with levels at or above 55 mg/dL. For patients with very well-controlled cholesterol, the treatment resulted in a lower rate of cardiovascular issues compared to a placebo, indicating its effectiveness even among those managing their cholesterol well.

While we did find that icosapent ethyl could help manage cardiovascular risks in patients with heightened cholesterol, it's essential to clarify that the study primarily focused on the rate of cardiovascular events rather than a direct impact purely on cholesterol levels. Overall, our findings suggest that even patients with optimal cholesterol control can still gain benefits from this treatment regarding cardiovascular health.
9
Antarctic krill oil aids cholesterol
We aimed to understand how Antarctic krill oil (ESKO) affects cholesterol levels, particularly in relation to obesity. Through our study involving mice, we observed that ESKO helped reduce oxidative stress and improve cholesterol metabolism.

While a high-fat diet usually worsens cholesterol levels, ESKO demonstrated a protective effect by reducing fat accumulation and promoting better metabolic health. This suggests that krill oil could be a promising option for managing high cholesterol and obesity-related issues.
9
Scallop oil significantly reduces cholesterol
We investigated how different oils, including newly produced scallop oil, fish oil, and krill oil, impact cholesterol levels in obese type II diabetic mice. Our study involved feeding these groups various high-fat diets for 42 days.

Remarkably, the scallop oil group showed a significant reduction in cholesterol levels in both serum and liver, while the fish oil and krill oil groups did not exhibit such benefits. The findings suggest that scallop oil might be a promising option for managing cholesterol and preventing related health issues.
9
High-purity EPA benefits cholesterol
We examined the impact of a highly purified eicosapentaenoic acid (EPA) formulation on cholesterol levels and overall heart health in individuals considered at high risk for cardiovascular issues. The study involved 226 patients who had high triglycerides and one or more cardiovascular risk factors, such as hypertension or diabetes.

Participants received 4 grams of EPA daily for three months alongside regular nutritional counseling. By tracking key health markers, we noted significant improvements in cholesterol levels, particularly in triglycerides and low-density lipoprotein (LDL). For instance, triglyceride levels dropped from an average of 2.97 mmol/L to 1.75 mmol/L in just three months.

Additionally, we found improvements in other important metrics, including total cholesterol and glucose levels, indicating that EPA supplementation may have broad benefits for cardiometabolic health. Although apolipoprotein A levels did not change significantly, the overall trend suggests that incorporating EPA could play a role in achieving better heart health outcomes.
We explored how eicosapentaenoic acid (EPA) impacts cholesterol, particularly focusing on its effects in patients with high triglyceride levels. Research indicates that hypertriglyceridaemia can contribute significantly to atherosclerotic cardiovascular disease (ASCVD), even in patients who have low levels of low-density lipoprotein cholesterol (LDL-C) due to treatments like statins.

While previous studies have shown mixed results regarding the effectiveness of triglyceride-lowering medications, EPA stands out in providing favorable outcomes for certain patient groups. It's worth noting that the combination of EPA with another substance, docosahexaenoic acid (DHA), has not demonstrated the same benefits.

The key takeaway is that while the search for efficient treatments continues, isolated EPA treatment has shown promise in reducing ASCVD risk, especially for patients struggling with high triglyceride levels. This suggests that as we develop our understanding of cholesterol management, EPA could be an important piece of the puzzle for those at risk.

References

  1. Choi JH, Park SE, Kim S. Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice. Nutrients. 2024;16. 10.3390/nu16213614
  2. Hirako S, Kim H, Iizuka Y, Matsumoto A. Fish oil consumption prevents hepatic lipid accumulation induced by high-cholesterol feeding in obese KK mice. Biomed Res. 2024;45:33. 10.2220/biomedres.45.33
  3. Mjaatveit M, Oldernes H, Gudbrandsen OA. Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis. Br J Nutr. 2024;131:606. 10.1017/S0007114523002118
  4. Zhang C, Wang X, Sun S, Fu Y, Wu Y, et al. Fat-1 expression alleviates atherosclerosis in transgenic rabbits. J Cell Mol Med. 2022;26:1306. 10.1111/jcmm.17188
  5. Sugimoto K, Hosomi R, Shimono T, Kanda S, Nishiyama T, et al. Comparison of the Cholesterol-Lowering Effect of Scallop Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis), Fish Oil, and Krill Oil in Obese Type II Diabetic KK-A Mice. J Oleo Sci. 2021;70:965. 10.5650/jos.ess21032
  6. Jaca A, Durão S, Harbron J. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. S Afr Med J. 2020;110:1158. 10.7196/SAMJ.2020.v110i12.14730
  7. Trivedi K, Le V, Nelson JR. The case for adding eicosapentaenoic acid (icosapent ethyl) to the ABCs of cardiovascular disease prevention. Postgrad Med. 2021;133:28. 10.1080/00325481.2020.1783937
  8. Saito M, Ishida N, Yamada H, Ibi M, Hirose M. 8-HEPE-Concentrated Materials from Pacific Krill Improve Plasma Cholesterol Levels and Hepatic Steatosis in High Cholesterol Diet-Fed Low-Density Lipoprotein (LDL) Receptor-Deficient Mice. Biol Pharm Bull. 2020;43:919. 10.1248/bpb.b20-00162
  9. Llop-Talaveron J, Badía-Tahull M, Lozano-Andreu T, Rigo-Bonnin R, Virgili-Casas N, et al. Phytosterolemia and γ-glutamyl transferase in adults with parenteral nutrition: Fish versus vegetal lipids: A randomized clinical trial. Nutrition. 2020;70:110587. 10.1016/j.nut.2019.110587
  10. Antona ME, Ramos C, Stranges A, Monteiro AF, Gonzales Chaves MM, et al. Fish oil diet effects on alveolar bone loss, in hypercholesterolemic rats. Arch Oral Biol. 2020;109:104553. 10.1016/j.archoralbio.2019.104553
  11. Zhou Q, Zhang Z, Wang P, Zhang B, Chen C, et al. EPA+DHA, but not ALA, Improved Lipids and Inflammation Status in Hypercholesterolemic Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Mol Nutr Food Res. 2019;63:e1801157. 10.1002/mnfr.201801157
  12. Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, et al. Effects of Icosapent Ethyl on Total Ischemic Events: From REDUCE-IT. J Am Coll Cardiol. 2019;73:2791. 10.1016/j.jacc.2019.02.032
  13. Preston Mason R. New Insights into Mechanisms of Action for Omega-3 Fatty Acids in Atherothrombotic Cardiovascular Disease. Curr Atheroscler Rep. 2019;21:2. 10.1007/s11883-019-0762-1
  14. Vikøren LA, Drotningsvik A, Bergseth MT, Mjøs SA, Austgulen MH, et al. Intake of Baked Cod Fillet Resulted in Lower Serum Cholesterol and Higher Long Chain -3 PUFA Concentrations in Serum and Tissues in Hypercholesterolemic Obese Zucker fa/fa Rats. Nutrients. 2018;10. 10.3390/nu10070840
  15. Blom WAM, Koppenol WP, Hiemstra H, Stojakovic T, Scharnagl H, et al. A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia. Eur J Nutr. 2019;58:1615. 10.1007/s00394-018-1706-1
  16. Shen J, Rastogi R, Guan L, Li F, Du H, et al. Omega-3 fatty acid supplement reduces activation of NADPH oxidase in intracranial atherosclerosis stenosis. Neurol Res. 2018;40:499. 10.1080/01616412.2018.1451290
  17. Yunoki K, Matsumi H, Miyoshi T, Kubo M, Hata Y, et al. Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy. J Cardiovasc Dev Dis. 2025;12. 10.3390/jcdd12020060
  18. Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
  19. Uthaiah NM, Venkataramareddy SR, Mudhol S, Sheikh AY. EPA-rich Nannochloropsis oceanica biomass regulates gut microbiota, alleviates inflammation and ameliorates liver fibrosis in rats. Food Res Int. 2025;202:115733. 10.1016/j.foodres.2025.115733
  20. Yoshikiyo K, Shimizu H, Nagato EG, Ishizuka S, Yamamoto T. Comparative Analysis of γ-Cyclodextrin, Perilla Oil, and Their Inclusion Complexes on Liver Injury and Dyslipidemia Associated with Elevated Gastrointestinal 12-Hydroxylated Bile Acid Levels. Molecules. 2025;30. 10.3390/molecules30020281
  21. Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, et al. EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors. Sci Rep. 2024;14:27146. 10.1038/s41598-024-73672-6
  22. Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. 10.3389/fnut.2024.1423228
  23. Bashir B, Schofield J, Downie P, France M, Ashcroft DM, et al. Beyond LDL-C: unravelling the residual atherosclerotic cardiovascular disease risk landscape-focus on hypertriglyceridaemia. Front Cardiovasc Med. 2024;11:1389106. 10.3389/fcvm.2024.1389106
  24. Lin YL, Wang CL, Chiang TI. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients. Front Nephrol. 2024;4:1365809. 10.3389/fneph.2024.1365809
  25. Omari M, Alkhalil M. Atherosclerosis Residual Lipid Risk-Overview of Existing and Future Pharmacotherapies. J Cardiovasc Dev Dis. 2024;11. 10.3390/jcdd11040126
  26. Szarek M, Bhatt DL, Miller M, Brinton EA, Jacobson TA, et al. Lipoprotein(a) Blood Levels and Cardiovascular Risk Reduction With Icosapent Ethyl. J Am Coll Cardiol. 2024;83:1529. 10.1016/j.jacc.2024.02.016
  27. Liakos CI, Lanaras L, Bristianou M, Papadopoulos DP. Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals. Lipids. 2024;59:67. 10.1002/lipd.12391
  28. Ganuza E, Etomi EH, Olson M, Whisner CM. Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population. Front Nutr. 2024;11:1293909. 10.3389/fnut.2024.1293909
  29. Kobayashi Y, Fujikawa T, Haruna A, Kawano R, Ozawa M, et al. Omega-3 Fatty Acids Reduce Remnant-like Lipoprotein Cholesterol and Improve the Ankle-Brachial Index of Hemodialysis Patients with Dyslipidemia: A Pilot Study. Medicina (Kaunas). 2023;60. 10.3390/medicina60010075
  30. Mueller PA, Bergstrom P, Rosario S, Heard M, Pamir N. Fish Oil Supplementation Modifies the Proteome, Lipidome, and Function of High-Density Lipoprotein: Findings from a Trial in Young Healthy Adults. J Nutr. 2024;154:1130. 10.1016/j.tjnut.2024.01.007
  31. Kaur G, Mason RP, Steg PG, Bhatt DL. Omega-3 fatty acids for cardiovascular event lowering. Eur J Prev Cardiol. 2024;31:1005. 10.1093/eurjpc/zwae003
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